Presence of basic fibroblast growth factor in the early embryo
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چکیده
منابع مشابه
Presence of basic fibroblast growth factor in the early Xenopus embryo
Mesoderm-inducing activity can be extracted from Xenopus embryos, eggs or whole ovary. It binds to heparin and can be neutralized by heparin or anti-bFGF but not by anti-TGF/?. Two molecular forms can be identified by Western blotting and have molecular weights of about 19 and 14K. The content in embryos is about 7 units g~' (approximately 7 ng ml~*) which would be sufficient for it to be actin...
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BACKGROUND Tendon injuries are common and it takes a long time for an injured tendon to heal. Adverse phenomena such as adhesion and rupture are associated with these injuries. Finding a method to reduce the time required for healing whichimproves the final outcome, will lead to decreased frequency and intensity of adverse consequences. This study was designed to investigate the effects ...
متن کاملBasic fibroblast growth factor promotes the development of human ovarian early follicles during growth in vitro.
STUDY QUESTION What is the effect of basic fibroblast growth factor (bFGF) on the growth of individual early human follicles in a three-dimensional (3D) culture system in vitro? SUMMARY ANSWER The addition of 200 ng bFGF/ml improves human early follicle growth, survival and viability during growth in vitro. WHAT IS KNOWN ALREADY It has been demonstrated that bFGF enhances primordial follicl...
متن کاملBasic fibroblast growth factor in the chick embryo: immunolocalization to striated muscle cells and their precursors
The identification of acidic and basic fibroblast growth factors (FGFs) in a number of embryonic tissue extracts has implicated these growth factors in the regulation of a variety of embryonic events including angiogenesis, eye development, and muscle differentiation. Lack of information concerning the cellular distribution of the growth factor within these tissues has made it extremely difficu...
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Background Fertility preservation is an important part of scientific study in the field of reproductive medicine. Ovarian cryopreservation and in vitro follicles culture provide option for fertility conservation in older women or cancer patients. Basic fibroblast growth factor (bFGF) or FGF-2, is member of fibroblast growth factors family which play critical roles in cell migration proliferatio...
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ژورنال
عنوان ژورنال: Development
سال: 1989
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.105.1.147